NAD+ is a coenzyme found in every living cell and is essential for energy production and cellular function. Researchers are interested in NAD+ because it plays a central role in metabolism, mitochondrial activity, DNA repair, and healthy aging research.
Scientific Information
- Full Name: Nicotinamide Adenine Dinucleotide (Oxidized Form)
- Molecular Formula: C21H27N7O14P2
- Molecular Weight: ~663.4 Daltons
- Structure: NAD+ is a coenzyme composed of two nucleotides joined through their phosphate groups. It functions as a key electron carrier in cellular energy metabolism.
Research & Potential Benefits
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Cellular Energy Production:
NAD+ is central to redox reactions and energy production, making it a major focus in mitochondrial and metabolic research. (Reference 1, 2) -
Healthy Aging Research:
Researchers study NAD+ because declining levels have been associated with aging and age-related physiological changes. (Reference 1, 3) -
DNA Repair & Cellular Maintenance:
NAD+ supports enzymes involved in DNA repair, stress response, and broader cellular maintenance pathways. (Reference 2, 4) -
Metabolic Function:
NAD+ has been widely studied for its role in glucose metabolism, mitochondrial health, and overall metabolic resilience. (Reference 2, 3)
References
- Lautrup, S. et al. “Roles of NAD+ in Health and Aging.” Cell Metabolism.
- Covarrubias, A.J. et al. “NAD+ metabolism and its roles in cellular processes during ageing.” Nature Reviews Molecular Cell Biology.
- Yaku, K. et al. “NAD metabolism: Implications in aging and longevity.” Ageing Research Reviews.
- Bhasin, S. et al. “Nicotinamide Adenine Dinucleotide in Aging Biology.” Journal of Clinical Endocrinology & Metabolism.
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